James Watson, a prominent and often contentious figure in science, co-won the Nobel Prize for uncovering the structure of DNA. As an American molecular biologist, he shared the 1962 Nobel Prize in Physiology or Medicine for identifying DNA's structure and its critical role in transmitting genetic information within living organisms.
This breakthrough was monumental, revealing the mechanisms genes use and fostering the development of molecular biology and evolutionary phylogenetics. It has deeply influenced many scientists’ careers, including those leading bioinformatics and functional genomics research.
Watson was known for his outspoken nature and transformed science communication by providing the public with an unfiltered, personal view into the ruthless and competitive environment of scientific research. He was the first prominent Nobel laureate to do so.
Entering the University of Chicago at just 15, Watson originally planned to be an ornithologist. His direction shifted after reading Erwin Schrödinger’s book What is Life?, which discusses the chemistry and physics of cellular processes. This sparked his curiosity about the composition of genes, then the largest mystery in biology.
At that time, chromosomes were known to contain both protein and DNA and were identified as the molecules responsible for heredity.
"What is Life?"
Author's summary: James Watson's pioneering discovery of DNA's structure reshaped biology and science communication, leaving a lasting legacy fueled by curiosity and boldness.