Three Infections, One Fight: Implementation Study in Regina, Saskatchewan
Introduction
Saskatchewan is experiencing a significant public health emergency characterized by high rates of HIV, syphilis, and hepatitis C virus (HCV) infections. The situation is especially severe among people who inject drugs, where stigma, poverty, and restricted access to culturally appropriate healthcare amplify the challenges. Addressing these syndemic infections demands innovative, community-driven interventions that enhance prevention, testing, and connectivity to care.
Methods and Analysis
The study introduces a rapid assessment and response model in Regina, Saskatchewan, Canada, combining geospatial analysis of needle distribution with on-the-ground outreach. Using detailed needle hotspot maps, researchers will direct mobile community events that provide point-of-care testing for HIV, syphilis, and HCV. These sessions will also include educational resources on pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP).
Evaluation Framework
The project follows a convergent participatory mixed-methods design guided by the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework. This approach will measure the initiative’s practicality, community acceptance, and overall impact.
Quantitative Assessment
- Changes in awareness and use of PrEP and PEP
- Participant satisfaction with the intervention
- Demographic profiling and documentation of new infection diagnoses
Qualitative Substudy
A parallel qualitative component involving 30 participants will explore personal experiences with the outreach program. It will focus on perceived barriers to accessing healthcare, engagement with services, and participants’ understanding of prevention strategies.
“Needle hotspot maps will be used to guide the deployment of community-based pop-up events offering point-of-care testing for HIV, syphilis and HCV.”
Author Summary
This study pioneers a real-time, community-focused model in Regina, integrating data mapping with mobile interventions to reduce transmission of HIV, syphilis, and HCV among vulnerable populations.