Research has identified familial clustering in primary hyperparathyroidism, indicating that first-degree relatives are at a higher risk than control patients.
A study published in the Journal of the Endocrine Society found that first-degree relatives of patients with primary hyperparathyroidism are more likely to develop the condition themselves.
Previous research suggested a link between primary hyperparathyroidism and an increased risk of malignancy, with a pooled prevalence of 20% for any type of cancer among this population.
However, it was unclear whether first-degree relatives of patients with primary hyperparathyroidism are at increased risk for cancer or the thyroid condition.
A link to cancer risk among parents, siblings, and children is less certain.
Author's summary: Familial clustering found in primary hyperparathyroidism.