Familial Clustering Identified in Primary Hyperparathyroidism

Familial Clustering in Primary Hyperparathyroidism

Research has identified familial clustering in primary hyperparathyroidism, indicating that first-degree relatives are at a higher risk than control patients.

A study published in the Journal of the Endocrine Society found that first-degree relatives of patients with primary hyperparathyroidism are more likely to develop the condition themselves.

Previous research suggested a link between primary hyperparathyroidism and an increased risk of malignancy, with a pooled prevalence of 20% for any type of cancer among this population.

However, it was unclear whether first-degree relatives of patients with primary hyperparathyroidism are at increased risk for cancer or the thyroid condition.

A link to cancer risk among parents, siblings, and children is less certain.

Author's summary: Familial clustering found in primary hyperparathyroidism.

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Rheumatology Advisor Rheumatology Advisor — 2025-10-30