Scientists at the University of Glasgow have developed a new machine learning model to translate the language of proteins using a powerful supercomputer.
The cross-disciplinary team created a large language model (LLM) called PLM-Interact to understand protein interactions and predict which mutations will impact how proteins interact with each other.
The new study, published in Nature Communications, shows that PLM-Interact outperforms competing models in understanding and predicting protein interactions.
Early tests of PLM-Interact, a protein language model (PLM), demonstrate its potential in better understanding protein interactions.
Author's summary: Scientists use AI to understand proteins.